Differentiated human stem cells resemble fetal, not adult, β cells

Human pluripotent stem cells (hPSCs) have the potential to generate any human cell type, and one widely recognized goal is to make pancreatic β cells. To this end, comparisons between differentiated cell types produced in vitro and their in vivo counterparts are essential to validate hPSC-derived ce...

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Главные авторы: Hrvatin, Sinisa, O’Donnell, Charles W., Deng, Francis, Millman, Jeffrey R., Pagliuca, Felicia Walton, DiIorio, Philip, Rezania, Alireza, Gifford, David K., Melton, Douglas A.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2014
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3939927/
https://ncbi.nlm.nih.gov/pubmed/24516164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1400709111
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