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How to make a functional β-cell

Insulin-secreting pancreatic β-cells are essential regulators of mammalian metabolism. The absence of functional β-cells leads to hyperglycemia and diabetes, making patients dependent on exogenously supplied insulin. Recent insights into β-cell development, combined with the discovery of pluripotent...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pagliuca, Felicia W., Melton, Douglas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666377/
https://ncbi.nlm.nih.gov/pubmed/23715541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.093187
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