Death-Domain-Receptor 3 Deletion Normalizes Inflammatory Gene Expression and Prevents Ileitis in Experimental Crohn’s Disease

BACKGROUND: TNF-like cytokine 1A (TL1A) and its functional receptor, death-domain-receptor-3 (DR3), are multifunctional mediators of effector and regulatory immunity. We aimed to evaluate the functional role and therapeutic potential of TL1A/DR3 signaling in Crohn’s disease–like ileitis. METHODS: Il...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Buttó, Ludovica F, Jia, Li-Guo, Arseneau, Kristen O, Tamagawa, Hiroshi, Rodriguez-Palacios, Alex, Li, Zhaodong, De Salvo, Carlo, Pizarro, Theresa T, Bamias, Giorgos, Cominelli, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Leading off
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290789/
https://ncbi.nlm.nih.gov/pubmed/30295722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ibd/izy305
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados