Specific Modification of Aged Proteasomes Revealed by Tag-Exchangeable Knock-In Mice

The proteasome is the proteolytic machinery at the center of regulated intracellular protein degradation and participates in various cellular processes. Maintaining the quality of the proteasome is therefore important for proper cell function. It is unclear, however, how proteasomes change over time...

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Publicat a:Mol Cell Biol
Autors principals: Tomita, Takuya, Hirayama, Shoshiro, Sakurai, Yasuyuki, Ohte, Yuki, Yoshihara, Hidehito, Saeki, Yasushi, Hamazaki, Jun, Murata, Shigeo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290375/
https://ncbi.nlm.nih.gov/pubmed/30348842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00426-18
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