載入...
Enhanced O-GlcNAcylation Mediates Cytoprotection under Proteasome Impairment by Promoting Proteasome Turnover in Cancer Cells
The proteasome is a therapeutic target in cancer, but resistance to proteasome inhibitors often develops owing to the induction of compensatory pathways. Through a genome-wide siRNA screen combined with RNA sequencing analysis, we identified hexokinase and downstream O-GlcNAcylation as cell survival...
Na minha lista:
| 發表在: | iScience |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2020
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7338785/ https://ncbi.nlm.nih.gov/pubmed/32634741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101299 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|