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Specific Modification of Aged Proteasomes Revealed by Tag-Exchangeable Knock-In Mice

The proteasome is the proteolytic machinery at the center of regulated intracellular protein degradation and participates in various cellular processes. Maintaining the quality of the proteasome is therefore important for proper cell function. It is unclear, however, how proteasomes change over time...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Tomita, Takuya, Hirayama, Shoshiro, Sakurai, Yasuyuki, Ohte, Yuki, Yoshihara, Hidehito, Saeki, Yasushi, Hamazaki, Jun, Murata, Shigeo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290375/
https://ncbi.nlm.nih.gov/pubmed/30348842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00426-18
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