The structures of penicillin-binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into β-lactam resistance

The final steps of cell-wall biosynthesis in bacteria are carried out by penicillin-binding proteins (PBPs), whose transpeptidase domains form the cross-links in peptidoglycan chains that define the bacterial cell wall. These enzymes are the targets of β-lactam antibiotics, as their inhibition reduc...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Moon, Thomas M., D'Andréa, Éverton D., Lee, Christopher W., Soares, Alexei, Jakoncic, Jean, Desbonnet, Charlene, Garcia-Solache, Monica, Rice, Lou B., Page, Rebecca, Peti, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290140/
https://ncbi.nlm.nih.gov/pubmed/30355734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006052
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados