The structures of penicillin-binding protein 4 (PBP4) and PBP5 from Enterococci provide structural insights into β-lactam resistance

The final steps of cell-wall biosynthesis in bacteria are carried out by penicillin-binding proteins (PBPs), whose transpeptidase domains form the cross-links in peptidoglycan chains that define the bacterial cell wall. These enzymes are the targets of β-lactam antibiotics, as their inhibition reduc...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Moon, Thomas M., D'Andréa, Éverton D., Lee, Christopher W., Soares, Alexei, Jakoncic, Jean, Desbonnet, Charlene, Garcia-Solache, Monica, Rice, Lou B., Page, Rebecca, Peti, Wolfgang
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2018
Предметы:
Enzymology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290140/
https://ncbi.nlm.nih.gov/pubmed/30355734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006052
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы