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Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

Recombination, the exchange of information between different genetic polymer strands, is of fundamental importance in biology for genome maintenance and genetic diversification and is mediated by dedicated recombinase enzymes. Here, we describe an innate capacity for non-enzymatic recombination (and...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Mutschler, Hannes, Taylor, Alexander I, Porebski, Benjamin T, Lightowlers, Alice, Houlihan, Gillian, Abramov, Mikhail, Herdewijn, Piet, Holliger, Philipp
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289569/
https://ncbi.nlm.nih.gov/pubmed/30461419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43022
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