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Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

Recombination, the exchange of information between different genetic polymer strands, is of fundamental importance in biology for genome maintenance and genetic diversification and is mediated by dedicated recombinase enzymes. Here, we describe an innate capacity for non-enzymatic recombination (and...

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Pubblicato in:eLife
Autori principali: Mutschler, Hannes, Taylor, Alexander I, Porebski, Benjamin T, Lightowlers, Alice, Houlihan, Gillian, Abramov, Mikhail, Herdewijn, Piet, Holliger, Philipp
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289569/
https://ncbi.nlm.nih.gov/pubmed/30461419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43022
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