CNS Langerhans Cell Histiocytosis: Common Hematopoietic Origin for LCH-Associated Neurodegeneration and Mass Lesions

BACKGROUND: Central nervous system Langerhans cell histiocytosis (CNS-LCH) brain involvement may include mass lesions and/or a neurodegenerative disease (LCH-ND) of unknown etiology. The goal of this study was to define the mechanisms of pathogenesis that drive CNS-LCH. METHODS: Cerebrospinal fluid...

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Publicado no:Cancer
Main Authors: McClain, Kenneth L., Picarsic, Jennifer, Chakraborty, Rikhia, Zinn, Daniel, Lin, Howard, Abhyankar, Harshal, Scull, Brooks, Shih, Albert, Phaik Har Lim, Karen, Eckstein, Olive, Lubega, Joseph, Peters, Tricia L., Olea, Walter, Burke, Thomas, Ahmed, Nabil, John Hicks, M., Tran, Brandon, Jones, Jeremy, Dauser, Robert, Jeng, Michael, Baiocchi, Robert, Schiff, Deborah, Goldman, Stanton, Heym, Kenneth M., Wilson, Harry, Carcamo, Benjamin, Kumar, Ashish, Rodriguez-Galindo, Carlos, Whipple, Nicholas S., Campbell, Patrick, Murdoch, Geoffrey, Kofler, Julia, Heales, Simon, Malone, Marian, Woltjer, Randy, Quinn, Joseph F., Orchard, Paul, Kruer, Michael C., Jaffe, Ronald, Manz, Markus G., Lira, Sergio A., Williams Parsons, D., Merad, Miriam, Man, Tsz-Kwong, Allen, Carl E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289302/
https://ncbi.nlm.nih.gov/pubmed/29624648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31348
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