CNS Langerhans Cell Histiocytosis: Common Hematopoietic Origin for LCH-Associated Neurodegeneration and Mass Lesions

BACKGROUND: Central nervous system Langerhans cell histiocytosis (CNS-LCH) brain involvement may include mass lesions and/or a neurodegenerative disease (LCH-ND) of unknown etiology. The goal of this study was to define the mechanisms of pathogenesis that drive CNS-LCH. METHODS: Cerebrospinal fluid...

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Veröffentlicht in:Cancer
Hauptverfasser: McClain, Kenneth L., Picarsic, Jennifer, Chakraborty, Rikhia, Zinn, Daniel, Lin, Howard, Abhyankar, Harshal, Scull, Brooks, Shih, Albert, Phaik Har Lim, Karen, Eckstein, Olive, Lubega, Joseph, Peters, Tricia L., Olea, Walter, Burke, Thomas, Ahmed, Nabil, John Hicks, M., Tran, Brandon, Jones, Jeremy, Dauser, Robert, Jeng, Michael, Baiocchi, Robert, Schiff, Deborah, Goldman, Stanton, Heym, Kenneth M., Wilson, Harry, Carcamo, Benjamin, Kumar, Ashish, Rodriguez-Galindo, Carlos, Whipple, Nicholas S., Campbell, Patrick, Murdoch, Geoffrey, Kofler, Julia, Heales, Simon, Malone, Marian, Woltjer, Randy, Quinn, Joseph F., Orchard, Paul, Kruer, Michael C., Jaffe, Ronald, Manz, Markus G., Lira, Sergio A., Williams Parsons, D., Merad, Miriam, Man, Tsz-Kwong, Allen, Carl E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289302/
https://ncbi.nlm.nih.gov/pubmed/29624648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31348
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