Circulating CD1c(+) myeloid dendritic cells are potential precursors to LCH lesion CD1a(+)CD207(+) cells

Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder that is characterized by the inflammatory lesions with pathogenic CD1a(+)CD207(+) dendritic cells (DCs). BRAFV600E and other somatic activating MAPK gene mutations have been identified in differentiating bone marrow and blood myelo...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Lim, Karen Phaik Har, Milne, Paul, Poidinger, Michael, Duan, Kaibo, Lin, Howard, McGovern, Naomi, Abhyankar, Harshal, Zinn, Daniel, Burke, Thomas M., Eckstein, Olive S., Chakraborty, Rikhia, Sengal, Amel, Scull, Brooks, Newell, Evan, Merad, Miriam, McClain, Kenneth L., Man, Tsz-Kwong, Ginhoux, Florent, Collin, Matthew, Allen, Carl E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960472/
https://ncbi.nlm.nih.gov/pubmed/31899802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000488
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