Circulating CD1c(+) myeloid dendritic cells are potential precursors to LCH lesion CD1a(+)CD207(+) cells

Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder that is characterized by the inflammatory lesions with pathogenic CD1a(+)CD207(+) dendritic cells (DCs). BRAFV600E and other somatic activating MAPK gene mutations have been identified in differentiating bone marrow and blood myelo...

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Bibliografski detalji
Izdano u:Blood Adv
Glavni autori: Lim, Karen Phaik Har, Milne, Paul, Poidinger, Michael, Duan, Kaibo, Lin, Howard, McGovern, Naomi, Abhyankar, Harshal, Zinn, Daniel, Burke, Thomas M., Eckstein, Olive S., Chakraborty, Rikhia, Sengal, Amel, Scull, Brooks, Newell, Evan, Merad, Miriam, McClain, Kenneth L., Man, Tsz-Kwong, Ginhoux, Florent, Collin, Matthew, Allen, Carl E.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2020
Teme:
Myeloid Neoplasia
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6960472/
https://ncbi.nlm.nih.gov/pubmed/31899802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000488
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