Bone Marrow-Derived CD4(+) T Cells Are Depleted in Simian Immunodeficiency Virus-Infected Macaques and Contribute to the Size of the Replication-Competent Reservoir

The bone marrow (BM) is the key anatomic site for hematopoiesis and plays a significant role in the homeostasis of mature T cells. However, very little is known on the phenotype of BM-derived CD4(+) T cells, their fate during simian immunodeficiency virus (SIV) infection, and their contribution to v...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hoang, Timothy N., Harper, Justin L., Pino, Maria, Wang, Hong, Micci, Luca, King, Colin T., McGary, Colleen S., McBrien, Julia B., Cervasi, Barbara, Silvestri, Guido, Paiardini, Mirko
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288341/
https://ncbi.nlm.nih.gov/pubmed/30305357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01344-18
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