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Identification of Antinorovirus Genes in Human Cells Using Genome-Wide CRISPR Activation Screening
Noroviruses (NoVs) are a leading cause of gastroenteritis worldwide, yet host factors that restrict NoV replication are not well understood. Here, we use a CRISPR activation genome-wide screening to identify host genes that can inhibit murine norovirus (MNoV) replication in human cells. Our screens...
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| Vydáno v: | J Virol |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6288323/ https://ncbi.nlm.nih.gov/pubmed/30305350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01324-18 |
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