Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells

Distinct protein phosphorylation levels in interphase and M phase require tight regulation of Cdk1 activity [1, 2]. A bistable switch, based on positive feedback in the Cdk1 activation loop, has been proposed to generate different thresholds for transitions between these cell-cycle states [3, 4, 5]....

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Curr Biol
Main Authors: Rata, Scott, Suarez Peredo Rodriguez, Maria F., Joseph, Stephy, Peter, Nisha, Echegaray Iturra, Fabio, Yang, Fengwei, Madzvamuse, Anotida, Ruppert, Jan G., Samejima, Kumiko, Platani, Melpomeni, Alvarez-Fernandez, Monica, Malumbres, Marcos, Earnshaw, William C., Novak, Bela, Hochegger, Helfrid
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287978/
https://ncbi.nlm.nih.gov/pubmed/30449668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.09.059
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker