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HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry
The chromosomal passenger complex (CPC) is directed to centromeres during mitosis via binding to H3T3ph and Sgo1. Whether and how heterochromatin protein 1α (HP1α) influences CPC localisation and function during mitotic entry is less clear. Here, we alter HP1α dynamics by fusing it to a CENP‐B DNA‐b...
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| Опубликовано в: : | EMBO J |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5852645/ https://ncbi.nlm.nih.gov/pubmed/29467217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797677 |
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