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HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry

The chromosomal passenger complex (CPC) is directed to centromeres during mitosis via binding to H3T3ph and Sgo1. Whether and how heterochromatin protein 1α (HP1α) influences CPC localisation and function during mitotic entry is less clear. Here, we alter HP1α dynamics by fusing it to a CENP‐B DNA‐b...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Ruppert, Jan G, Samejima, Kumiko, Platani, Melpomeni, Molina, Oscar, Kimura, Hiroshi, Jeyaprakash, A Arockia, Ohta, Shinya, Earnshaw, William C
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852645/
https://ncbi.nlm.nih.gov/pubmed/29467217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797677
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