A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus

Tcrb locus V(D)J recombination is regulated by positioning at the nuclear periphery. Here, we used DamID to profile Tcrb locus interactions with the nuclear lamina at high resolution. We identified a lamina-associated domain (LAD) border composed of several CTCF-binding elements that segregates acti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Chen, Shiwei, Luperchio, Teresa Romeo, Wong, Xianrong, Doan, Europe B., Byrd, Aaron T., Choudhury, Kingshuk Roy, Reddy, Karen L., Krangel, Michael S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287930/
https://ncbi.nlm.nih.gov/pubmed/30428344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.052
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