A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus

Tcrb locus V(D)J recombination is regulated by positioning at the nuclear periphery. Here, we used DamID to profile Tcrb locus interactions with the nuclear lamina at high resolution. We identified a lamina-associated domain (LAD) border composed of several CTCF-binding elements that segregates acti...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Chen, Shiwei, Luperchio, Teresa Romeo, Wong, Xianrong, Doan, Europe B., Byrd, Aaron T., Choudhury, Kingshuk Roy, Reddy, Karen L., Krangel, Michael S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287930/
https://ncbi.nlm.nih.gov/pubmed/30428344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.052
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