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Nucleosome positions establish an extended mutation signature in melanoma
Ultraviolet (UV) light-induced mutations are unevenly distributed across skin cancer genomes, but the molecular mechanisms responsible for this heterogeneity are not fully understood. Here, we assessed how nucleosome structure impacts the positions of UV-induced mutations in human melanomas. Analysi...
Tallennettuna:
| Julkaisussa: | PLoS Genet |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6287878/ https://ncbi.nlm.nih.gov/pubmed/30485262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007823 |
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