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ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma
Recurrent mutations are frequently associated with transcription factor (TF) binding sites (TFBS) in melanoma, but the mechanism driving mutagenesis at TFBS is unclear. Here, we use a method called CPD-seq to map the distribution of UV-induced cyclobutane pyrimidine dimers (CPDs) across the human ge...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6035183/ https://ncbi.nlm.nih.gov/pubmed/29980679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05064-0 |
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