HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy

Through whole-transcriptome profiling of HER2+ breast carcinomas (BCs), we previously showed that those sensitive to trastuzumab are addicted to this oncoprotein and are enriched in immune pathways, raising the hypothesis that HER2 itself regulates immune cell recruitment. In the present study we in...

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書目詳細資料
發表在:Oncoimmunology
Main Authors: Triulzi, Tiziana, Forte, Luca, Regondi, Viola, Di Modica, Martina, Ghirelli, Cristina, Carcangiu, Maria Luisa, Sfondrini, Lucia, Balsari, Andrea, Tagliabue, Elda
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2018
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287794/
https://ncbi.nlm.nih.gov/pubmed/30546951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1512942
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