Taxanes enhance trastuzumab-mediated ADCC on tumor cells through NKG2D-mediated NK cell recognition

Recent clinical data indicate a synergistic therapeutic effect between trastuzumab and taxanes in neoadjuvantly treated HER2-positive breast cancer (BC) patients. In HER2+ BC experimental models and patients, we investigated whether this synergy depends on the ability of drug-induced stress to impro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Di Modica, Martina, Sfondrini, Lucia, Regondi, Viola, Varchetta, Stefania, Oliviero, Barbara, Mariani, Gabriella, Bianchi, Giulia Valeria, Generali, Daniele, Balsari, Andrea, Triulzi, Tiziana, Tagliabue, Elda
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807996/
https://ncbi.nlm.nih.gov/pubmed/26595802
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