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HER2 signaling regulates the tumor immune microenvironment and trastuzumab efficacy

Through whole-transcriptome profiling of HER2+ breast carcinomas (BCs), we previously showed that those sensitive to trastuzumab are addicted to this oncoprotein and are enriched in immune pathways, raising the hypothesis that HER2 itself regulates immune cell recruitment. In the present study we in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncoimmunology
Päätekijät: Triulzi, Tiziana, Forte, Luca, Regondi, Viola, Di Modica, Martina, Ghirelli, Cristina, Carcangiu, Maria Luisa, Sfondrini, Lucia, Balsari, Andrea, Tagliabue, Elda
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287794/
https://ncbi.nlm.nih.gov/pubmed/30546951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1512942
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