Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells

The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can function as in situ cancer vaccination by exposing tumor antigens and providing adjuvants for anti-tumor immune priming. In this regard, the mode of tumor cell death and the repertoire of released dam...

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Vydáno v:Oncoimmunology
Hlavní autoři: Krombach, Julia, Hennel, Roman, Brix, Nikko, Orth, Michael, Schoetz, Ulrike, Ernst, Anne, Schuster, Jessica, Zuchtriegel, Gabriele, Reichel, Christoph A., Bierschenk, Susanne, Sperandio, Markus, Vogl, Thomas, Unkel, Steffen, Belka, Claus, Lauber, Kirsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287777/
https://ncbi.nlm.nih.gov/pubmed/30546963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1523097
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