Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells

The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can function as in situ cancer vaccination by exposing tumor antigens and providing adjuvants for anti-tumor immune priming. In this regard, the mode of tumor cell death and the repertoire of released dam...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Krombach, Julia, Hennel, Roman, Brix, Nikko, Orth, Michael, Schoetz, Ulrike, Ernst, Anne, Schuster, Jessica, Zuchtriegel, Gabriele, Reichel, Christoph A., Bierschenk, Susanne, Sperandio, Markus, Vogl, Thomas, Unkel, Steffen, Belka, Claus, Lauber, Kirsten
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287777/
https://ncbi.nlm.nih.gov/pubmed/30546963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1523097
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