Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells

The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy can function as in situ cancer vaccination by exposing tumor antigens and providing adjuvants for anti-tumor immune priming. In this regard, the mode of tumor cell death and the repertoire of released dam...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Krombach, Julia, Hennel, Roman, Brix, Nikko, Orth, Michael, Schoetz, Ulrike, Ernst, Anne, Schuster, Jessica, Zuchtriegel, Gabriele, Reichel, Christoph A., Bierschenk, Susanne, Sperandio, Markus, Vogl, Thomas, Unkel, Steffen, Belka, Claus, Lauber, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287777/
https://ncbi.nlm.nih.gov/pubmed/30546963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1523097
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