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Expression of the IFNAR1 chain of type 1 interferon receptor in benign cells protects against progression of acute leukemia

Type I interferons (IFN) were widely used for leukemia treatment. These cytokines act on cell surface receptor consisting of the IFNAR1/2 chains to induce anti-tumorigenic effects. Given that levels of IFNAR1 can be regulated by phosphorylation-driven ubiquitination and degradation that undermines I...

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Bibliografiska uppgifter
I publikationen:Leuk Lymphoma
Huvudupphovsmän: Zhao, Bin, Bhattacharya, Sabyasachi, Yu, Qiujing, Fuchs, Serge Y.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287747/
https://ncbi.nlm.nih.gov/pubmed/28503979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2017.1319053
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