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Expression of the IFNAR1 chain of type 1 interferon receptor in benign cells protects against progression of acute leukemia
Type I interferons (IFN) were widely used for leukemia treatment. These cytokines act on cell surface receptor consisting of the IFNAR1/2 chains to induce anti-tumorigenic effects. Given that levels of IFNAR1 can be regulated by phosphorylation-driven ubiquitination and degradation that undermines I...
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| Gepubliceerd in: | Leuk Lymphoma |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6287747/ https://ncbi.nlm.nih.gov/pubmed/28503979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10428194.2017.1319053 |
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