Chronic Overexpression of Bradykinin in Kidney Causes Polyuria and Cardiac Hypertrophy

Acute intra-renal infusion of bradykinin increases diuresis and natriuresis via inhibition of vasopressin activity. However, the consequences of chronically increased bradykinin in the kidneys have not yet been studied. A new transgenic animal model producing an excess of bradykinin by proximal tubu...

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Bibliografske podrobnosti
izdano v:Front Med (Lausanne)
Main Authors: Barros, Carlos C., Schadock, Ines, Sihn, Gabin, Rother, Franziska, Xu, Ping, Popova, Elena, Lapidus, Irina, Plehm, Ralph, Heuser, Arnd, Todiras, Mihail, Bachmann, Sebastian, Alenina, Natalia, Araujo, Ronaldo C., Pesquero, Joao B., Bader, Michael
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Medicine
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287039/
https://ncbi.nlm.nih.gov/pubmed/30560131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00338
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