Chronic Overexpression of Bradykinin in Kidney Causes Polyuria and Cardiac Hypertrophy

Acute intra-renal infusion of bradykinin increases diuresis and natriuresis via inhibition of vasopressin activity. However, the consequences of chronically increased bradykinin in the kidneys have not yet been studied. A new transgenic animal model producing an excess of bradykinin by proximal tubu...

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Detalles Bibliográficos
Publicado en:Front Med (Lausanne)
Main Authors: Barros, Carlos C., Schadock, Ines, Sihn, Gabin, Rother, Franziska, Xu, Ping, Popova, Elena, Lapidus, Irina, Plehm, Ralph, Heuser, Arnd, Todiras, Mihail, Bachmann, Sebastian, Alenina, Natalia, Araujo, Ronaldo C., Pesquero, Joao B., Bader, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287039/
https://ncbi.nlm.nih.gov/pubmed/30560131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00338
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