Chronic Overexpression of Bradykinin in Kidney Causes Polyuria and Cardiac Hypertrophy

Acute intra-renal infusion of bradykinin increases diuresis and natriuresis via inhibition of vasopressin activity. However, the consequences of chronically increased bradykinin in the kidneys have not yet been studied. A new transgenic animal model producing an excess of bradykinin by proximal tubu...

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Detalles Bibliográficos
Publicado en:Front Med (Lausanne)
Autores principales: Barros, Carlos C., Schadock, Ines, Sihn, Gabin, Rother, Franziska, Xu, Ping, Popova, Elena, Lapidus, Irina, Plehm, Ralph, Heuser, Arnd, Todiras, Mihail, Bachmann, Sebastian, Alenina, Natalia, Araujo, Ronaldo C., Pesquero, Joao B., Bader, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
Materias:
Medicine
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287039/
https://ncbi.nlm.nih.gov/pubmed/30560131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00338
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