Chronic Overexpression of Bradykinin in Kidney Causes Polyuria and Cardiac Hypertrophy

Acute intra-renal infusion of bradykinin increases diuresis and natriuresis via inhibition of vasopressin activity. However, the consequences of chronically increased bradykinin in the kidneys have not yet been studied. A new transgenic animal model producing an excess of bradykinin by proximal tubu...

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Dettagli Bibliografici
Pubblicato in:Front Med (Lausanne)
Autori principali: Barros, Carlos C., Schadock, Ines, Sihn, Gabin, Rother, Franziska, Xu, Ping, Popova, Elena, Lapidus, Irina, Plehm, Ralph, Heuser, Arnd, Todiras, Mihail, Bachmann, Sebastian, Alenina, Natalia, Araujo, Ronaldo C., Pesquero, Joao B., Bader, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287039/
https://ncbi.nlm.nih.gov/pubmed/30560131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2018.00338
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