Rapamycin Enhances Mitophagy and Attenuates Apoptosis After Spinal Ischemia-Reperfusion Injury

The spinal cord is extremely vulnerable to ischemia-reperfusion (I/R) injury, and the mitochondrion is the most crucial interventional target. Rapamycin can promote autophagy and exert neuroprotective effects in several diseases of the central nervous system. However, the impact of rapamycin via mod...

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Dettagli Bibliografici
Pubblicato in:Front Neurosci
Autori principali: Li, Qiang, Gao, Shane, Kang, Zhanrong, Zhang, Meiyan, Zhao, Xin, Zhai, Yu, Huang, Jianming, Yang, Guo-Yuan, Sun, Wanju, Wang, Jian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286985/
https://ncbi.nlm.nih.gov/pubmed/30559639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00865
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