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Rapamycin Enhances Mitophagy and Attenuates Apoptosis After Spinal Ischemia-Reperfusion Injury

The spinal cord is extremely vulnerable to ischemia-reperfusion (I/R) injury, and the mitochondrion is the most crucial interventional target. Rapamycin can promote autophagy and exert neuroprotective effects in several diseases of the central nervous system. However, the impact of rapamycin via mod...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Li, Qiang, Gao, Shane, Kang, Zhanrong, Zhang, Meiyan, Zhao, Xin, Zhai, Yu, Huang, Jianming, Yang, Guo-Yuan, Sun, Wanju, Wang, Jian
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286985/
https://ncbi.nlm.nih.gov/pubmed/30559639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00865
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