Rapamycin Enhances Mitophagy and Attenuates Apoptosis After Spinal Ischemia-Reperfusion Injury

The spinal cord is extremely vulnerable to ischemia-reperfusion (I/R) injury, and the mitochondrion is the most crucial interventional target. Rapamycin can promote autophagy and exert neuroprotective effects in several diseases of the central nervous system. However, the impact of rapamycin via mod...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Li, Qiang, Gao, Shane, Kang, Zhanrong, Zhang, Meiyan, Zhao, Xin, Zhai, Yu, Huang, Jianming, Yang, Guo-Yuan, Sun, Wanju, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286985/
https://ncbi.nlm.nih.gov/pubmed/30559639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00865
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