Rapamycin Enhances Mitophagy and Attenuates Apoptosis After Spinal Ischemia-Reperfusion Injury

The spinal cord is extremely vulnerable to ischemia-reperfusion (I/R) injury, and the mitochondrion is the most crucial interventional target. Rapamycin can promote autophagy and exert neuroprotective effects in several diseases of the central nervous system. However, the impact of rapamycin via mod...

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Bibliografski detalji
Izdano u:Front Neurosci
Glavni autori: Li, Qiang, Gao, Shane, Kang, Zhanrong, Zhang, Meiyan, Zhao, Xin, Zhai, Yu, Huang, Jianming, Yang, Guo-Yuan, Sun, Wanju, Wang, Jian
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Neuroscience
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286985/
https://ncbi.nlm.nih.gov/pubmed/30559639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00865
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