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Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging

Replication-based telomere shortening during lifetime is species- and tissue-specific, however, its impact on healthy aging is unclear. In particular, the contribution of telomere truncation to the aging process of the CNS, where replicative senescence alone fails to explain organ aging due to low t...

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Podrobná bibliografie
Vydáno v:Aging (Albany NY)
Hlavní autoři: Ain, Quratul, Schmeer, Christian, Penndorf, Diane, Fischer, Mike, Bondeva, Tzvetanka, Förster, Martin, Haenold, Ronny, Witte, Otto W, Kretz, Alexandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286833/
https://ncbi.nlm.nih.gov/pubmed/30472697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101655
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