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Extrachromosomal Circular DNA: Current Knowledge and Implications for CNS Aging and Neurodegeneration

Still unresolved is the question of how a lifetime accumulation of somatic gene copy number alterations impact organ functionality and aging and age-related pathologies. Such an issue appears particularly relevant in the broadly post-mitotic central nervous system (CNS), where non-replicative neuron...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Ain, Quratul, Schmeer, Christian, Wengerodt, Diane, Witte, Otto W., Kretz, Alexandra
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177960/
https://ncbi.nlm.nih.gov/pubmed/32252492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072477
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