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Cell cycle-dependent and -independent telomere shortening accompanies murine brain aging

Replication-based telomere shortening during lifetime is species- and tissue-specific, however, its impact on healthy aging is unclear. In particular, the contribution of telomere truncation to the aging process of the CNS, where replicative senescence alone fails to explain organ aging due to low t...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Ain, Quratul, Schmeer, Christian, Penndorf, Diane, Fischer, Mike, Bondeva, Tzvetanka, Förster, Martin, Haenold, Ronny, Witte, Otto W, Kretz, Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286833/
https://ncbi.nlm.nih.gov/pubmed/30472697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101655
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