Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis

Left ventricular hypertrophy (LVH) is a major risk factor for cardiovascular morbidity and mortality. Pathological LVH engages transcriptional programs including reactivation of canonical fetal genes and those inducing fibrosis. Histone lysine demethylases (KDMs) are emerging regulators of transcrip...

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Zhang, Qing-Jun, Tran, Tram Anh T., Wang, Ming, Ranek, Mark J., Kokkonen-Simon, Kristen M., Gao, Jason, Luo, Xiang, Tan, Wei, Kyrychenko, Viktoriia, Liao, Lan, Xu, Jianming, Hill, Joseph A., Olson, Eric N., Kass, David A., Martinez, Elisabeth D., Liu, Zhi-Ping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286331/
https://ncbi.nlm.nih.gov/pubmed/30531796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07173-2
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