Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis

Left ventricular hypertrophy (LVH) is a major risk factor for cardiovascular morbidity and mortality. Pathological LVH engages transcriptional programs including reactivation of canonical fetal genes and those inducing fibrosis. Histone lysine demethylases (KDMs) are emerging regulators of transcrip...

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Publicado no:Nat Commun
Main Authors: Zhang, Qing-Jun, Tran, Tram Anh T., Wang, Ming, Ranek, Mark J., Kokkonen-Simon, Kristen M., Gao, Jason, Luo, Xiang, Tan, Wei, Kyrychenko, Viktoriia, Liao, Lan, Xu, Jianming, Hill, Joseph A., Olson, Eric N., Kass, David A., Martinez, Elisabeth D., Liu, Zhi-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286331/
https://ncbi.nlm.nih.gov/pubmed/30531796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07173-2
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