Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice

BACKGROUND: Effective targeting therapies for common chronic liver disease nonalcoholic steatohepatitis (NASH) are in urgent need. MicroRNA-targeted therapeutics would be potentially an effective treatment strategy of hepatic diseases. Here we investigated the functional role of miR-221/222 and the...

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Библиографические подробности
Опубликовано в: :EBioMedicine
Главные авторы: Jiang, Xiuli, Jiang, Lei, Shan, Aijing, Su, Yutong, Cheng, Yulong, Song, Dalong, Ji, He, Ning, Guang, Wang, Weiqing, Cao, Yanan
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2018
Предметы:
Research paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284352/
https://ncbi.nlm.nih.gov/pubmed/30316865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.09.051
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