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Targeting hepatic miR-221/222 for therapeutic intervention of nonalcoholic steatohepatitis in mice
BACKGROUND: Effective targeting therapies for common chronic liver disease nonalcoholic steatohepatitis (NASH) are in urgent need. MicroRNA-targeted therapeutics would be potentially an effective treatment strategy of hepatic diseases. Here we investigated the functional role of miR-221/222 and the...
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| Veröffentlicht in: | EBioMedicine |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6284352/ https://ncbi.nlm.nih.gov/pubmed/30316865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.09.051 |
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