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Genomic landscape of oxidative DNA damage and repair reveals regioselective protection from mutagenesis

BACKGROUND: DNA is subject to constant chemical modification and damage, which eventually results in variable mutation rates throughout the genome. Although detailed molecular mechanisms of DNA damage and repair are well understood, damage impact and execution of repair across a genome remain poorly...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genome Biol
Egile Nagusiak: Poetsch, Anna R., Boulton, Simon J., Luscombe, Nicholas M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6284305/
https://ncbi.nlm.nih.gov/pubmed/30526646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1582-2
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