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The genomics of oxidative DNA damage, repair, and resulting mutagenesis

Reactive oxygen species are a constant threat to DNA as they modify bases with the risk of disrupting genome function, inducing genome instability and mutation. Such risks are due to primary oxidative DNA damage and also mediated by the repair process. This leads to a delicate decision process for t...

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Pubblicato in:Comput Struct Biotechnol J
Autore principale: Poetsch, Anna R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Research Network of Computational and Structural Biotechnology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974700/
https://ncbi.nlm.nih.gov/pubmed/31993111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.12.013
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