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The genomics of oxidative DNA damage, repair, and resulting mutagenesis

Reactive oxygen species are a constant threat to DNA as they modify bases with the risk of disrupting genome function, inducing genome instability and mutation. Such risks are due to primary oxidative DNA damage and also mediated by the repair process. This leads to a delicate decision process for t...

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Détails bibliographiques
Publié dans:Comput Struct Biotechnol J
Auteur principal: Poetsch, Anna R.
Format: Artigo
Langue:Inglês
Publié: Research Network of Computational and Structural Biotechnology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6974700/
https://ncbi.nlm.nih.gov/pubmed/31993111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.12.013
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