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Genomic landscape of oxidative DNA damage and repair reveals regioselective protection from mutagenesis
BACKGROUND: DNA is subject to constant chemical modification and damage, which eventually results in variable mutation rates throughout the genome. Although detailed molecular mechanisms of DNA damage and repair are well understood, damage impact and execution of repair across a genome remain poorly...
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| Publié dans: | Genome Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6284305/ https://ncbi.nlm.nih.gov/pubmed/30526646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1582-2 |
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