Anilinoquinoline based inhibitors of trypanosomatid proliferation

We recently reported the medicinal chemistry re-optimization of a series of compounds derived from the human tyrosine kinase inhibitor, lapatinib, for activity against Plasmodium falciparum. From this same library of compounds, we now report potent compounds against Trypanosoma brucei brucei (which...

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Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: Ferrins, Lori, Sharma, Amrita, Thomas, Sarah M., Mehta, Naimee, Erath, Jessey, Tanghe, Scott, Leed, Susan E., Rodriguez, Ana, Mensa-Wilmot, Kojo, Sciotti, Richard J., Gillingwater, Kirsten, Pollastri, Michael P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283615/
https://ncbi.nlm.nih.gov/pubmed/30475800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006834
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