Anilinoquinoline based inhibitors of trypanosomatid proliferation

We recently reported the medicinal chemistry re-optimization of a series of compounds derived from the human tyrosine kinase inhibitor, lapatinib, for activity against Plasmodium falciparum. From this same library of compounds, we now report potent compounds against Trypanosoma brucei brucei (which...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Ferrins, Lori, Sharma, Amrita, Thomas, Sarah M., Mehta, Naimee, Erath, Jessey, Tanghe, Scott, Leed, Susan E., Rodriguez, Ana, Mensa-Wilmot, Kojo, Sciotti, Richard J., Gillingwater, Kirsten, Pollastri, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283615/
https://ncbi.nlm.nih.gov/pubmed/30475800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006834
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