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Incompatibilities in Mismatch Repair Genes MLH1-PMS1 Contribute to a Wide Range of Mutation Rates in Human Isolates of Baker’s Yeast
Laboratory baker’s yeast strains bearing an incompatible combination of MLH1 and PMS1 mismatch repair alleles are mutators that can adapt more rapidly to stress, but do so at the cost of long-term fitness. We identified 18 baker’s yeast isolates from 1011 surveyed that contain the incompatible MLH1-...
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| 出版年: | Genetics |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Genetics Society of America
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6283166/ https://ncbi.nlm.nih.gov/pubmed/30348651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301550 |
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