DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair
The yeast Mlh1–Pms1 heterodimer required for mismatch repair (MMR) binds to DNA. Here we map DNA binding to N-terminal fragments of Mlh1 and Pms1. We demonstrate that Mlh1 and Pms1 N-terminal domains (NTDs) independently bind to double-stranded and single-stranded DNA, in the absence of dimerization...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12682353/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg324 |
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