The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides

Amide bond formation is one of the most important reactions in pharmaceutical synthetic chemistry. The development of sustainable methods for amide bond formation, including those that are catalyzed by enzymes, is therefore of significant interest. The ATP‐dependent amide bond synthetase (ABS) enzym...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Petchey, Mark, Cuetos, Anibal, Rowlinson, Benjamin, Dannevald, Stephanie, Frese, Amina, Sutton, Peter W., Lovelock, Sarah, Lloyd, Richard C., Fairlamb, Ian J. S., Grogan, Gideon
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282839/
https://ncbi.nlm.nih.gov/pubmed/30035356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201804592
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