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Computational characterization of the binding mode between oncoprotein Ets‐1 and DNA‐repair enzymes

The Ets‐1 oncoprotein is a transcription factor that promotes target gene expression in specific biological processes. Typically, Ets‐1 activity is low in healthy cells, but elevated levels of expression have been found in cancerous cells, specifically related to tumor progression. Like the vast maj...

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Podrobná bibliografie
Vydáno v:Proteins
Hlavní autoři: de Ruyck, Jerome, Brysbaert, Guillaume, Villeret, Vincent, Aumercier, Marc, Lensink, Marc F.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282593/
https://ncbi.nlm.nih.gov/pubmed/30019773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25578
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